1,3-dimethyl-8-(3-methyl-1-piperidinyl)-7-[2-[(5-methyl-1,3,4-thiadiazol-2-yl)thio]ethyl]purine-2,6-dione

The compound you described, **1,3-dimethyl-8-(3-methyl-1-piperidinyl)-7-[2-[(5-methyl-1,3,4-thiadiazol-2-yl)thio]ethyl]purine-2,6-dione**, is a complex organic molecule with a long and descriptive chemical name. It's more commonly referred to by its code name, **BMS-214662**.

**BMS-214662 is a potent and selective antagonist of the adenosine A2A receptor.** Let's break down what that means:

* **Adenosine A2A Receptor:** This is a type of G protein-coupled receptor (GPCR) found in the brain and other tissues. It plays a role in various functions, including:
* **Neurotransmission:** Modulating the release of neurotransmitters like dopamine.
* **Inflammation:** Regulating inflammatory responses.
* **Cardiovascular health:** Affecting heart rate and blood pressure.

* **Antagonist:** This means BMS-214662 blocks the action of adenosine at the A2A receptor. It prevents adenosine from binding and activating the receptor.

**Why is BMS-214662 important for research?**

* **Potential Therapeutic Applications:** The ability of BMS-214662 to block the adenosine A2A receptor makes it a promising candidate for treating various conditions:
* **Parkinson's Disease:** Blocking A2A receptors can enhance dopamine signaling, potentially improving motor function.
* **Addiction:** A2A receptor antagonists show potential for reducing drug craving and withdrawal symptoms.
* **Inflammation:** Blocking A2A receptors can suppress inflammatory responses, potentially benefitting conditions like arthritis.
* **Cancer:** Some research suggests A2A receptor antagonists may have anti-tumor effects.

* **Understanding the Role of Adenosine:** Studying the effects of BMS-214662 helps researchers understand the complex roles of the adenosine A2A receptor in the body. This knowledge can be crucial for developing more targeted and effective treatments for various diseases.

**Important Note:** BMS-214662 is still in the research phase. While promising, it's important to note that it hasn't yet been approved for clinical use. More research is needed to determine its safety and efficacy for specific medical conditions.